What is Anafril?
Anafril (Generic name: clomipramine) is a tricyclic antidepressant used to treat symptoms of obsessive-compulsive disorder (OCD) such as repetitive actions and recurrent feelings or thoughts. The drug helps reduce persistent thoughts (obsessions) and the urge to perform repeated tasks (compulsions) that often interfere with normal daily life. Anafril belongs to a class of drugs called tricyclic antidepressants, and works by restoring balance of certain natural substances in the brain, such as serotonin.
Common Anafril Side Effects
Common side effects of Anafril include:
- Dry mouth
- Stomach upset
- Appetite changes
- Increased weight
- Blurred vision of vision changes
- Memory problems
- Sleep problems
- Trouble concentrating
- Difficulty having an orgasm
- Decreased sex drive
Serious Anafril Side Effects
Some of the serious side effects of Anafril include:
- Mental or mood changes – e.g. depression and confusion
- Unwanted breast milk production
- Enlarged or painful breasts
- Irregular and/or painful menstrual periods
- Ringing in the ears
- Muscle stiffness
- Trouble urinating
- Shaking or tremors
- Panic attacks
- Suicidal thoughts
You should report these symptoms to your doctor as soon as possible.
When Not to Take Anafril
You should avoid taking Anafril if you’re allergic to clomipramine (Anafril) or to similar antidepressants such as amoxapine, amitriptyline, desipramine, doxepin, imipramine, protriptyline, protriptyline or trimipramine.
You should also avoid using clomipramine is you’ve taken an MAO inhibitor in the past 14 days. MAO inhibitors include furazolidone, linezolid, isocarboxazid, phenelzine, selegiline, rasagiline, and tranylcypromine.
While on Anafril you should avoid eating grapefruit or drinking grapefruit juice unless your doctor instructs otherwise. Grapefruit can increase the amount of certain medications in your bloodstream, which could worsen the symptoms of Anafril side effects.
The adult starting dosage of Anafril is 25 mg per day and can be gradually increase to approximately 100 mg during the first 2 weeks. The maximum dosage is 250 mg daily. You should consult your doctor for pediatric or adolescent dosing.
Anafril During Pregnancy
You should only use Anafril during pregnancy only if it’s a prescription from your doctor. Newborns exposed to this drug during pregnancy may experience withdrawal symptoms or side effects. Inform your doctor if you notice shaking, feeding problems, jitteriness, fast breathing, or seizures in your newborn. The drug passes into breast milk and may have undesirable effects on a nursing infant. Therefore, it’s safe to consult your doctor before breastfeeding.